R&D

Shaping the Future of Therapeutic Innovation and Distinction

Science
Curogen is paving the way in the treatment landscape for autoimmune diseases with original, first-in-class drugs. Based on a strong scientific foundation, Curogen develops both small molecule drugs and biologics to address critical unmet needs in chronic and rare diseases. Curogen's science integrates cutting-edge, biomarker driven research to identify novel targets and selective binding aimed to enhance efficacy and improve patient outcomes.
Effective Novel Target

With high potency and specificity, our therapies deliver a strong therapeutic impact while maintaining low remission rates to maximize long-term disease control. Leveraging advanced target discovery approaches, we work to identify additional new targets to improve underserved treatment paradigms.

CR-Fc Platform
& Multiple Target Approach

Designed for rational combination therapies, our unique CR-Fc platform enhances treatment effectiveness by targeting multiple disease mechanisms. Our biologics feature extended half-lives, optimizing pharmacokinetics for sustained efficacy. Built on a distinctive platform, our drugs address multiple disease pathways and offer comprehensive and long-lasting treatment solutions.

Focused on Safety and Efficacy

Our biologic is designed to achieve precise immune modulation with a focus on minimizing infection risk. Early data from human PBMC studies suggest low immunogenicity, with low anti-drug antibody (ADA) levels observed in comparative evaluation. In addition, ongoing candida studies suggest the potential for a more favorable safety profile in terms of infection risk compared to existing commercial therapies, while maintaining comparable efficacy.

Convenient Administration

Our small molecule drugs are developed as oral formulations to enable seamless combination with other treatments and to enhance patient compliance.
Our biologics are developed as subcutaneous injection for long-term, sustained efficacy. New therapeutic candidates are continuously advanced to optimize treatment outcomes.